A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered

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Researchers from the group Mitochondrial regulation of cell death and steatohepatitis have revealed a new role for acid ceramidase (ACDase) in experimental models and in patients with NPC through the regulation of STARD1 and its impact on mitochondrial function.
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
Niemann–Pick type C disease: cellular pathology and pharmacotherapy - Wheeler - 2020 - Journal of Neurochemistry - Wiley Online Library
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
Niemann–Pick Disease Type C
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
NPC1 - Wikipedia
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation - ScienceDirect
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease - ScienceDirect
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC),  discovered
UPR analysis in NPC mice cerebellum. a NPC and wildtype (WT) mice were
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